How much is the bus ticket from Durham to Syracuse?

The cheapest bus tickets from Durham to Syracuse start from $96. The average price for this route is around $188. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Durham to Syracuse?

The average bus trip duration from Durham to Syracuse is 18h, covering a distance of 510 miles (822 km). The quickest bus can get you there in 17h 50m and is operated by FlixBus .

Which bus companies service the Durham to Syracuse route?

Several major bus companies operate on this route with 4 buses available per day, including services from FlixBus , Greyhound .

What is the earliest and latest departure time for the bus from Durham to Syracuse?

The earliest bus departs from Durham to Syracuse at 2:40am. And the latest bus departs at 9:15pm.

What are the CO₂ emissions for the bus trip from Durham to Syracuse?

A bus trip from Durham to Syracuse generates an estimated 20.5347 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Durham to Syracuse?

According to Busbud customers, the highest-rated bus company on this route is FlixBus , with an average rating of 3.5 out of 5 stars based on 12517 reviews.

Which bus company has the best Wi-Fi from Durham to Syracuse?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Durham to Syracuse?

According to Busbud traveler reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 4.0 out of 5 stars.

Which bus company has the cleanest buses from Durham to Syracuse?

According to Busbud traveler reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Durham to Syracuse from $88 | Refundable Tickets

Next bus departures

Next departures for Durham to Syracuse on May 4
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
FlixBus + Greyhound Lines, Inc. + FlixBus	Bus	9:15pm	Durham	18h	3:15pm	Syracuse (Regional Transportation Center)	CheapestFastest

Last refresh of the prices: Yesterday at 3:22 PM EDT.

Compare 2 ways to go from Durham to Syracuse

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Syracuse. The journey takes about 18 hours and with fares starting at just $96, it presents an excellent value for a comfortable ride.

4bus per day

18hAverage Duration

510 milesDistance

21kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$96 - $353	Average Duration18h	CO₂ emissions 21kg CO₂e
Train	Average Price$163 - $311	Average Duration1d 3h	CO₂ emissions 75kg CO₂e

Where are the popular stops in Durham and Syracuse?

Stops in Durham

A
Durham Greyhound Bus Station
515 W Pettigrew St , Durham, NC 27703
Visit page
B
Compare Foods Durham
2000-2004 NC-55, Durham, NC 27704, USA
C
Durham Compare Foods Durham
2000 Avondale Dr, Durham, NC 27704, USA
D
Durham, NC
E Main St at Roxboro St (WB), Durham, NC 27701, USA

Stops in Syracuse

A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208
Visit page
B
Syracuse Airport
Visit page
C
Syracuse University
Bus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
Visit page
D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA
E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA
F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA

Compare bus companies

FlixBus

3.5/512,582 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,549 reviews

Staff3.6

Timeliness2.9

Cleanliness3.4

Wifi2.5

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies:FlixBus, Greyhound, Futura, Elite, Chihuahuenses, Tufesa, Valley Transit

Frequently asked questions about traveling from Durham, NC, US to Syracuse, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Durham to Syracuse?
The cheapest bus tickets from Durham to Syracuse start from $96. The average price for this route is around $188. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Durham to Syracuse?
The average bus trip duration from Durham to Syracuse is 18h, covering a distance of 510 miles (822 km). The quickest bus can get you there in 17h 50m and is operated by FlixBus.
Which bus companies service the Durham to Syracuse route?
Several major bus companies operate on this route with 4 buses available per day, including services from FlixBus, Greyhound.
What is the earliest and latest departure time for the bus from Durham to Syracuse?
The earliest bus departs from Durham to Syracuse at 2:40am. And the latest bus departs at 9:15pm.
What are the CO₂ emissions for the bus trip from Durham to Syracuse?
A bus trip from Durham to Syracuse generates an estimated 20.5347 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Durham to Syracuse?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 12517 reviews.
Which bus company has the best Wi-Fi from Durham to Syracuse?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Durham to Syracuse?
According to Busbud traveler reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Durham to Syracuse?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

05/02

No data

05/03

No data

Today

$146

05/05

No data

05/06

No data

05/07

No data

05/08

$91

05/09

No data

The cheapest trip from Durham, NC, US to Syracuse, US was searched and found on May 8, 2026 with a price of $91

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Syracuse, US, as early as possible.

You can expect to pay from $91 to $148 for a bus ticket from Durham, NC, US to Syracuse, US based on the last 2 days. You can expect to find the cheapest price for the trip at $91 which is on 2026-05-08.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.